Therapy with immune checkpoint inhibitors has become a new therapeutic option for several types of cancer, but immune-related adverse events can limit their use. 1 Outside of clinical studies, ...

A new study reports for the first time that injection of neuropeptide vasoactive intestinal peptide (VIP) directly into the eye of mice enhanced corneal graft survival. A new study in the American ...

The neuropeptide vasoactive intestinal peptide (VIP) has been shown to inhibit macrophage proinflammatory actions, promote a positive Th2/Th1 balance, and stimulate regulatory T-cell production. The ...

In an investigation published in this issue, Zhang et al. 6 use a mouse model to study the effects of IMD in relation to the important clinical problem of myocardial ischemia–reperfusion injury. The ...

Proceedings of the National Academy of Sciences of the United States of America, Vol. 70, No. 2 (Feb., 1973), pp. 382-384 (3 pages) An octacosapeptide with the entire sequence proposed for the newly ...

The pathobiology of pulmonary arterial hypertension (PAH) is complex and is not understood completely (1). Several abnormal signaling pathways have been identified, involving the three layers of the ...

New research published in JAMA Network Open highlights one potential cause of migraine. Although the exact underlying mechanisms of migraine remain unknown, research has revealed the condition is “a ...

Use of vasoactive intestinal peptide (VIP) to treat critical COVID-19 respiratory failure in patients with comorbidities has shown promise. Researchers presented findings from a prospective, ...

A study published in July 2020 hypothesized a link between the presence of bradykinin, a well-known peptide, and severe cases of COVID-19. Vardan Karamyan, Ph.D., an associate professor and vice chair ...

Dr. Schmaier’s major investigative work is on the vascular biology of the plasma kallikrein/kinin (KKS) and rennin angiotensin (RAS) systems. The Schmaier laboratory recognized that the endothelial ...