Coming into the 2024 NFL season, it wouldn't have been out of the ordinary to find a Super Bowl prediction featuring the ...

SportsLine's model has simulated San Francisco vs. Buffalo on Sunday Night Football 10,000 times and revealed its SNF picks ...

The Game Matchups Preview series is dedicated to breaking down how the Buffalo Bills match up with their opponent in every ...

The San Francisco 49ers battle the Buffalo Bills at 5:20 p.m. PDT on Sunday, Dec. 1 at Highmark  Stadium in Orchard Park, N.Y ...

Following new injury reports, updated simulations reveal the best bet for 49ers vs. Bills on Sunday Night Football. Injury ...

Defensively, two of the 49ers’ best players this season are out and will not travel as defensive end Nick Bosa (obliques, ...

Heavy snow is expected in Erie County, New York, this weekend, including when the AFC East-leading Bills host the 49ers for ...

A light dusting of snow began covering the Buffalo Bills' facility on Friday as the team completed its final practice of the ...

The San Francisco 49ers have released their final injury report ahead of their Week 13 bout with the Buffalo Bills.

The Bills put out a public call for snow shovelers with heavy lake effect snowfall in the forecast leading up to kickoff.

Heavy, lake-effect snow will fall on Buffalo this weekend as the 49ers arrive to face the Bills on Sunday night in the suburb ...

The San Francisco 49ers are bracing for snow ahead of Sunday's game in Buffalo, but new forecasts are painting a hopeful ...