The San Francisco 49ers may again be without starting quarterback Brock Purdy for their Week 13 clash with the San Francisco ...

Watch out for the tables on "Sunday Night Football." The nightcap of Sunday's action will be in northern New York with the Buffalo Bills (9-2) hosting the San Francisco 49ers (5-6). San Francisco has ...

The San Francisco 49ers are reportedly hoping that quarterback Brock Purdy's shoulder injury isn't a long-term issue, but ...

We’ve come that beloved point in the pro football season where the annual Thanksgiving Day games are upon us. Ahh yes, a day where we can gorge on food and ...

Being without Brock Purdy against the Green Bay Packers stung the San Francisco 49ers. It essentially chalked up the game as a loss for the 49ers before they ev ...

Should I drop Deebo Samuel for fantasy football Week 13? Is Deebo Samuel a safe player to cut? Read the fantasy football ...

San Francisco 49ers quarterback Brock Purdy is the latest star to receive a positive "PupTalk" from the characters of Nickelodeon's PAW Patrol.

The 49ers travel to Buffalo to take on the AFC East-leading Buffalo Bills. Check out our best bet for the game ...

San Francisco 49ers quarterback and Iowa State alum Brock Purdy is showing promising signs after being injured on Nov. 17.

Getting blown out at Green Bay following another squandered late lead the previous week against Seattle has quickly turned ...

San Francisco 49ers head coach Kyle Shanahan spoke with reporters via a conference call on Monday, providing several injury ...

San Francisco has put up a combined 27 points the past two weeks and faces a Bills defense great at generating pressure with ...