Sovereignty outdueled 3-1 favorite Journalism down the stretch to win the 151st Kentucky Derby in the slop on Saturday.

A Wisconsin man has been bitten by snakes hundreds of times, and scientists are studying his blood to treat snakebite.

Saturday and Monday will be the final two days to vote early ahead of the May 6 elections for Crown Point and Hobart school ...

A Russian drone strike on Kharkiv, Ukraine’s second-largest city, wounded 47 people, officials said, and prompted another appeal from Ukrainian President Volodymyr Zelenskyy for more decisive support ...

Get a recap of recent financial, health and general interest stories through this special edition of our Hot off the Wire ...

Ukrainian President Volodymyr Zelensky issued a dramatic warning to world leaders planning to attend Russia’s Victory Day ...

The Seattle-based coffee giant with more than 17,000 locations nationwide has never had a store quite like the one opening this week.

Millions of coins spilled onto a Texas highway this week after a tractor-trailer hauling $800,000 in dimes rolled over in an ...

NBC has done five hours of coverage on the main network on Derby Day since 2018. Sam Flood, the executive producer and ...

From Mexican meat markets in East Chicago to upscale cantinas in Valpo, The Region is ready for a May 5 Fiesta.

Guinness World Records certified world's tallest and smallest dogs met up for a playdate. Reginald, a 7-year-old Great Dane from Idaho, is the size of a small horse. Pearl, a ...

Health advocates are applauding Hoosier lawmakers for raising Indiana's cigarette tax by $2 per pack beginning July 1 — even if the tax hike mostly is to generate additional state revenue and ...