Researchers from the University of Eastern Finland, Aalto University and the University of Oulu have developed a new ...

New research predicts the location of DNA sequences that can form structures besides the canonical double helix — non-B DNA — in the recently released telomere-to-telomere genomes of the great apes, ...

Certain DNA sequences can form structures other than the canonical double helix. These alternative DNA conformations—referred ...

A key feature of cancer cells is their forced proliferation, which causes a hasty uncontrolled start of DNA replication. To date, however, little is known about the mechanisms that control the start ...

This study provides valuable findings on the role of site-specific DNA methylation changes during spermatogenesis and their contribution to paternal epigenetic inheritance. The study proposes that ...

The added stress causes cells to make errors copying their DNA, enabling cancer to gain a foothold and spread. "Transcription-replication ... to confirm proof of concept for whether exploiting ...

These essential enzymes maintain genome integrity and play a vital role in DNA replication and repair across all living organisms. By forming phosphodiester bonds, it ensures the seamless connection ...

To remedy this, local researchers are using a new class of DNA-based tracers to map the flow path of the aquifer. The tracers will be capsules made of environmentally safe material to ensure ...

Division of Physical Biology, CAS Key Laboratory of Interfacial Physics and Technology, Shanghai Institute of Applied Physics, Chinese Academy of Sciences, Shanghai 201800, China University of Chinese ...

We show that saccharin mediates its antimicrobial activity via bulge-mediated cell lysis rather than through impacting DNA replication dynamics ... We provide proof-of-concept results for the use of ...