The pain relievers acetaminophen and ibuprofen are in several over-the-counter drugs. Some people even mistake the two. But they have specific purposes and can cause problems if you’re not careful.

Taking Tylenol (acetaminophen) together with anti-inflammatory drugs like Aleve (naproxen) or Advil (ibuprofen) is generally considered safe, as long as you don't exceed recommended dosages.

DayQuil Cold & Flu is a multi-purpose medication used to treat common cold and flu symptoms. DayQuil ingredients include a fever and pain reducer (acetaminophen), cough suppressant (dextromethorphan), ...

Common pain relievers such as aspirin, ibuprofen, and acetaminophen don’t help much with cluster headaches, so your doctor may suggest one or more of the following treatments: Oxygen therapy.