It’s been a year since the gene-editing treatment Casgevy was approved for sickle cell disease and a related blood disorder.

Researchers led by Osaka University in Japan have conducted the first human trial using induced pluripotent stem-cell-derived ...

Human induced pluripotent stem cells (iPSCs) have a great potential for scientific and medical applications. They are used in ...

Researchers found that neural crest stem cells are uniquely capable of reprogramming, challenging current reprogramming ...

Skeletal stem cells have been isolated from various tissues, including periosteum and bone marrow, where they exhibit key functions in bone biology and hematopoiesis, respectively. The role of ...

Here, we show that hematopoiesis in the mice with Wbp1l germline deletion is dysregulated, already at the level of hematopoietic stem cells and early progenitors. We further demonstrate that thymi of ...

Age significantly influences stem cell survival and immune diversity, according to new research on the long-term behavior of ...

REFRaME-P1 is a registration-enabling study evaluating the efficacy and safety of luvelta in infants and children under 12 years of age with CBF/GLIS AML. This will be a global study, with the ...

Cardiovascular diseases remain the leading cause of mortality globally, encompassing a range of disorders that affect the heart and blood vessels, including but not limited to ischemic heart disease, ...

Stem cells are specialized cells that have the potential to develop into not one but many different types of cell. They are unlike any other cell for three specific reasons: They are unspecialized, ...

This subjects the donor cells to a fair amount of replicative stress. Some scientists are concerned that this stress could lead to clonal hematopoiesis, a phenomenon where the donated stem cells ...