Violent 12 hours on Indianapolis' east side leave one dead, three critically hurt, and multiple others injured. No arrests made.

The Detroit Lions are hoping to earn their ninth-straight victory over another quality opponent in the Indianapolis Colts. The Colts provide a different challenge than Detroit has seen in weeks past, ...

INDIANAPOLIS -- The Detroit Lions will look to keep up their winning ways on Sunday as they face a hungry Indianapolis Colts ...

The siblings both needed the same operation because of a birth defect that can cause the skull to grow abnormally.

INDIANAPOLIS — One person is left injured after an early ... Anyone with information on this incident is asked to contact ...

Veteran quarterback Daniel Jones is expected to clear waivers this week and quickly sign with a new team following his release from the New York Giants, NFL Network Insider Ian Rapoport reports.

An investigation is underway after a shooting left one person dead and one person critically injured early Sunday ...

The NFL Week 12 schedule features seven division games including the first place Arizona Cardinals (6-4) at the Seattle ...

When do the Colts play the Lions in NFL Week 12? Start the day smarter. Get all the news you need in your inbox each morning.

Drayton Jones had 23 points in South Carolina State's 72-62 victory over IU Indianapolis on Saturday. Jones also contributed seven rebounds for the Bulldogs (4-3). Colin McKenzie finished 3 of 4 from ...

Learn which TV channel or how to live stream the NFL Week 12 Indianapolis Colts and Detroit Lions game, Sunday, Nov. 24.

When it comes to their playoff odds, the Indianapolis Colts are among the teams with the most to gain, as well as lose, in ...