However, they are not completely safe to use during pregnancy as methimazole increases risk of neonatal malformations and propylthiouracil increases risk of maternal hepatotoxicity.

Other, much less common complications associated with PTU and methimazole are migratory polyarthritis, lupus-like syndrome, and cholestatic jaundice.

Learn about natural treatments and home remedies for hypothyroidism. This article also discusses when a person needs medical treatment.