The No. 21 Iowa State Cyclones (2-0) and the Arkansas State Red Wolves (2-1) square off at Jack Trice Stadium on Saturday, ...

Analyzing Saturday’s USC at Michigan odds and lines, with college football expert picks, predictions and best bets.

Following a 28-18 win over Arkansas State, No. 18 Michigan (2-1) faces its second Top 12 opponent in three weeks when it welcomes No. 11 USC (2-0) to the Big House this Saturday (3:30 p.m. ET / CBS).

Get tickets to see the USC Trojans take on the Michigan Wolverines in Ann Arbor, Saturday, Sept. 21, at 3:30pm. SeatGeek, ...

While USC will enter Saturday's game against Michigan relatively settled, the Wolverines are still ironing things out on a ...

The No. 12 USC Trojans (2-0) will play a fellow Big Ten opponent, the No. 17 Michigan Wolverines (2-1), in a matchup on ...

SportsLine's Jimmie Kaylor revealed his Week 4 CFB picks, predictions and props for the Michigan Wolverines vs. USC Trojans ...

Our USC vs. Michigan betting preview, odds and predictions focus on the favorite Trojans (-5.5) in Saturday's Big Ten matchup ...

Michigan will be making a quarterback change, benching Davis Warren for Alex Orji, despite a recent victory over Arkansas ...

The Michigan Wolverines have made a key adjustment at the quarterback position as they’re moving on from previous starter Davis Warren and inserting Alex Orji ahead of their USC matchup as they enter ...