Simon Says isn’t just a game, it’s a window into early HD! In this study, tiny thumb twitches reveal how attention slips ...

Scientists used 3D mini-brains grown from stem cells to study Huntington’s disease. They found early developmental changes ...

Participants in a PET study received the tracer, then gave it time to reach the brain. Then they laid in a scanner that took ...

On June 2, 2025, uniQure shared that they’re aligned with the FDA about moving forward with their HTT-lowering gene therapy, AMT‑130. If the next round of results from their ongoing trial continues to ...

TRACK-HD reveals significant changes in pre-symptomatic HD mutation carriers and patients The one-year report from the TRACK-HD study demonstrates a number of changes in pre-symptomatic HD-mutation ...

Minocycline: the end of the road? DOMINO clinical trial result: minocycline doesn’t slow down HD and shouldn’t be studied in larger trials.

Picture a quiet neighborhood. Things used to run smoothly here. Kids played outside, front yards were mowed, and the neurons — the longtime residents — looked out for one another. But lately, fires ...

Spark and Roche issued a joint community letter to share that the first patient has been dosed in a new HD gene therapy trial.

Huntington’s disease research news. In plain language. Written by scientists. For the global HD community.

Huntington’s disease research news. In plain language. Written by scientists. For the global HD community.

The latest instalment in a series of big studies to understand the genetics of Huntington disease (HD) just hit the shelves. These studies have focused on how small changes in the genetic letters of a ...