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  1. Aldosterone Suppression - Labcorp

    Protocol: The patient should consume a high salt diet supplemented with sodium chloride tablets (12 g/day) for three days. Starting on the morning of the third day, a 24-hour urine should be collected …

  2. Diagnosis of primary aldosteronism - UpToDate

    Oct 8, 2025 · Autonomous (primary) hypersecretion of aldosterone is an underdiagnosed cause of hypertension. The classic presenting signs of primary aldosteronism are hypertension and …

  3. Confirmatory Testing | Primary Aldosteronism Foundation

    To demonstrate this, patients are administered agents which suppress the regulator of aldosterone production. Hormones and electrolytes are measured before and after the test. If aldosterone is …

  4. Discordance and shortcomings of aldosterone suppression tests in ...

    Aug 29, 2025 · New guidelines recommend using these tests to predict the likelihood of unilateral PA. This study evaluated the diagnostic accuracy, consistency, and clinical implications of these tests.

  5. How the Saline Suppression Test Diagnoses Aldosteronism

    Nov 14, 2025 · The saline suppression test (SST) is a specialized diagnostic procedure used in endocrinology to investigate the body’s regulation of the hormone aldosterone.

  6. Is It Time to Retire Aldosterone Suppression Testing?

    Aug 28, 2025 · Given the clinical value of a PA diagnosis and the high prevalence of the disease, modern evidence suggests that aldosterone suppression testing should now be retired from the …

  7. The test is used to diagnose a condition called primary hyperaldosteronism (also known as Conn’s syndrome) which causes the body to produce increased amounts of aldosterone, leading to high …

  8. Confirmatory testing of primary aldosteronism with saline infusion test ...

    The current Clinical Practice Guideline of the Endocrine Society recommends screening by determination of the aldosterone/renin ratio (ARR) (1). Confirmatory testing can be accomplished by …

  9. Primary Aldosteronism Workup - Medscape

    Routine laboratory studies can show hypernatremia, hypokalemia, and metabolic alkalosis resulting from the action of aldosterone on the renal distal convoluted tubule (DCT) (ie, enhancing sodium...

  10. Pathology Outlines - Saline suppression test

    Feb 1, 2010 · Urine levels: collect 24 hour urine for aldosterone, creatinine (to assess the adequacy of urine collection), and sodium (to ensure adequate intake) on the last day of sodium chloride …