BRCA Gene Changes: Cancer Risk and Genetic Testing
Because harmful BRCA changes found in the tumor may have been inherited or may have arisen later in someone’s lifetime, someone with such a change in their tumor should consider getting …
BRCA1 and BRCA2 (PDQ®) - NCI - National Cancer Institute
Key points: BRCA1/2 -associated ovarian cancers are more likely to have high-grade serous adenocarcinoma histologies. Occult lesions found in the fallopian tubes of BRCA carriers …
Discovery – BRCA Connection to Breast and Ovarian Cancer
As a result of NCI's investment, people with a family history of breast and ovarian cancer can use their BRCA test results to help make informed decisions about screening and potential risk …
Hoja informativa sobre los cambios en el gen BRCA y las pruebas …
Los cambios dañinos en BRCA que se detectan en el tumor pueden ser hereditarios o haber surgido en otro momento de la vida de la persona. Por este motivo, si se identifica un cambio …
MRI, Surgery Reduce Cancer Deaths in Women with BRCA Changes
Apr 15, 2024 · For women with inherited harmful changes in BRCA genes, MRI surveillance and salpingo-oophorectomy can modestly reduce their risk of dying from breast and ovarian …
Genetic Testing Fact Sheet - NCI - National Cancer Institute
As of January 2024, the only FDA-approved DTC genetic test for inherited cancer risk tests for three different BRCA gene variants that are common in people of Ashkenazi Jewish descent.
Cancer Risk for Women Carrying BRCA Mutations - NCI
Jul 12, 2017 · An international team of researchers has published results from the first large prospective study of breast and ovarian cancer risk in women who carry inherited BRCA …
Olaparib for Pancreatic Cancer with BRCA Mutations - NCI
Jun 26, 2019 · Testing for BRCA mutations must be done using an FDA-approved test. The approval was based on results from the POLO clinical trial, which are described in the article …
Surgery to Reduce the Risk of Breast Cancer Fact Sheet
Jan 31, 2025 · People with a harmful BRCA variant who have surgery to treat breast cancer may also consider having risk-reducing salpingo-oophorectomy to improve their long-term outcomes.
Breast Cancer Risk Assessment Calculator - NCI
Enter the required information to calculate a patient's absolute risk for developing breast cancer. Created by the scientist at the National Cancer Institute and the NSABP.