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  1. Pembrolizumab for Early Triple-Negative Breast Cancer

    Feb 26, 2020 · In the KEYNOTE-522 trial, we evaluated the effect of neoadjuvant treatment on pathological complete response at the time of definitive surgery as well as the effect of both …

  2. You are going to start on a chemotherapy treatment plan called KEYNOTE-522. 2 parts. Your provider may reverse the sequence in which the 2 parts are given. There are 2 parts to this …

  3. KEYNOTE-522 - Clinical Trial Results | HCP - keytrudahcp.com

    Health care professionals may view findings from KEYNOTE-522, a clinical trial for patients with high-risk early-stage triple-negative breast cancer (TNBC).

  4. Event-free survival by residual cancer burden with pembrolizumab …

    Feb 16, 2024 · KEYNOTE-522 is the first prospective, phase III, randomized controlled study of pembrolizumab in patients with early-stage TNBC in the neoadjuvant and adjuvant settings.

  5. Neoadjuvant pembrolizumab plus chemotherapy/adjuvant …

    Oct 1, 2024 · Background: In KEYNOTE-522 (NCT03036488), neoadjuvant pembrolizumab plus chemotherapy and then adjuvant pembrolizumab significantly improved pathological complete …

  6. Pembrolizumab Plus Chemotherapy Followed by Pembrolizumab …

    Nov 15, 2023 · In this secondary analysis of patients enrolled in KEYNOTE-522 in East and Southeast Asia, neoadjuvant pembrolizumab plus chemotherapy followed by adjuvant …

  7. Merck Announces Phase 3 KEYNOTE-522 Trial Met its Overall …

    May 28, 2024 · KEYNOTE 522 is the fourth study of a KEYTRUDA-based regimen in an earlier stage of cancer to demonstrate an OS benefit, in addition to KEYNOTE-A18 in cervical cancer, …

  8. Overall Survival with Pembrolizumab in Early-Stage Triple …

    Sep 15, 2024 · In patients with early-stage triple-negative breast cancer, the phase 3 KEYNOTE-522 trial showed significant improvements in pathological complete response and event-free …

  9. Real-World Outcomes with the KEYNOTE-522 Regimen in Early …

    Abstract Background. This study aimed to determine if the neoadjuvant (NAT) KEYNOTE-522 regimen was associated with higher rates of pathologic complete response (pCR), …

  10. Overall Survival Analysis Confirms Pembrolizumab Regimen as …

    Oct 25, 2024 · For women with early-stage triple-negative breast cancer, KEYNOTE-522 changed the treatment paradigm several years ago.