The clinical heterogeneity of prostate cancer is a reflection of its molecular heterogeneity and the emergence of lineage plasticity, which is the ability of neoplastic cells to switch between …

Despite the prevalence and high mortality associated with prostate cancer, its pathophysiology is not well understood. This is because prostate cancer arises out of a complex interplay of risk …

Oct 25, 2024 · The review aims to update readers on the latest developments in the pathophysiology and management of prostate cancer. It covers recent research on the …

May 26, 2025 · This article aims to provide a comprehensive overview of the complexities of prostate cancer pathophysiology, including risk factors, molecular mechanisms, and disease …

Now, although the cause of prostate cancer is unknown, it's linked to a genetic mutation in a prostate cell, such as the BRCA1 and BRCA2 genes.

Identify the etiology of prostate cancer. Apply the underlying pathophysiology of prostate cancer to evaluation strategies. Select appropriate therapies, including hormonal treatments, …

In prostate cancer, the cells of these prostate glands mutate into cancer cells.The prostate gland require male hormones, known as androgen,to work properly.

Mar 3, 2022 · A 74 year old man with urinary hesitancy was found to have a PSA of 8 ng/mL. He had a transrectal ultrasound (TRUS) and prostate biopsy. A representative image is above. …

Nov 14, 2025 · High PSA? Don’t panic - it's not always cancer. Get the facts on what PSA levels mean, why they rise, and how benign prostate enlargement (BPH) connects to prostate cancer …

The review aims to update readers on the latest develop-ments in the pathophysiology and management of prostate cancer. It covers recent research on the disease's molecular …