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1. In 1953, James Watson and Francis Crick built their model of the structure of DNA, the principal features of which are still accepted today. DNA consists of two strands that are complementary in base sequences to each other. A cytosine base in one strand always pairs with a guanine base in the other. An adenine base in one strand always pairs with a thymine base in the other. 2. The complementary nature of the two strands suggested to the scientists a model for DNA replication. They proposed
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